EVALUATION OF THE QUALITY OF ALBENDAZOLE-BASED MEDICINES SEIZED ON THE ILLICIT MARKET IN CÔTE D’IVOIRE

  • Alain Aka KACOU Teaching Unit of Therapeutic and Organic Chemistry, Faculty of Pharmaceutical and Biological Sciences, Felix Houphouet Boigny University
  • Deto Ursul Jean Paul N'GUESSAN Teaching Unit of Therapeutic and Organic Chemistry, Faculty of Pharmaceutical and Biological Sciences, Felix Houphouet Boigny University, Côte d’Ivoire
  • Amelanh SICA DIAKITE Teaching Unit of Therapeutic and Organic Chemistry, Faculty of Pharmaceutical and Biological Sciences, Felix Houphouet Boigny University, Côte d’Ivoire
  • Songuigama COULIBALY Teaching Unit of Therapeutic and Organic Chemistry, Faculty of Pharmaceutical and Biological Sciences, Felix Houphouet Boigny University, Côte d’Ivoire
  • Adouko E. Teaching Unit of Therapeutic and Organic Chemistry, Faculty of Pharmaceutical and Biological Sciences, Felix Houphouet Boigny University, Côte d’Ivoire
  • Avi KT Teaching Unit of Therapeutic and Organic Chemistry, Faculty of Pharmaceutical and Biological Sciences, Felix Houphouet Boigny University, Côte d’Ivoire
  • Koffi F Teaching Unit of Therapeutic and Organic Chemistry, Faculty of Pharmaceutical and Biological Sciences, Felix Houphouet Boigny University, Côte d’Ivoire
  • Ouattara M Teaching Unit of Therapeutic and Organic Chemistry, Faculty of Pharmaceutical and Biological Sciences, Felix Houphouet Boigny University, Côte d’Ivoire

Abstract

Introduction Substandard and falsified medicines pose a global threat, particularly in sub-Saharan Africa where approximately 10 % of consumed medicines fall into this category. In Côte d’Ivoire, such products are often sold in open-air street markets. Among these, antiinfectives—especially antiparasitics like albendazole—are commonly encountered. Method This study assessed the quality of albendazole in medicines seized by the Directorate of Narcotics and Drugs Control (DPSD) using the GPHF-Minilab® kit, a portable quality-control tool. Results : Of the 15 samples analyzed, 14 exhibited anomalies on visual inspection, 33 % failed disintegration criteria, and 33 % had an assay of active ingredient outside acceptable limits. These findings highlight public health risks associated with consuming these products and underscore the need to strengthen quality-control measures. They also confirm the value of the GPHF-Minilab® in resource-limited settings.

Keywords: GPHF-Minilab®, Albendazole, Substandard, Falsified medicine

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How to Cite
KACOU, A., D. U. N’GUESSAN, A. SICA DIAKITE, S. COULIBALY, A. E., A. KT, K. F, and O. M. “EVALUATION OF THE QUALITY OF ALBENDAZOLE-BASED MEDICINES SEIZED ON THE ILLICIT MARKET IN CÔTE D’IVOIRE”. Journal of Applied Pharmaceutical Sciences and Research, Vol. 8, no. 3, Nov. 2025, pp. 31-34, doi:10.31069/japsr.v8i3.05.
Section
Research Articles