INCIDENCE OF ACUTE KIDNEY INJURY IN ACUTE GASTROENTERITIS PATIENTS PRESENTING TO SHEIKH ZAYED UNIVERSITY TEACHING HOSPITAL KHOST, AFGHANISTAN
Abstract
Backgroud: Acute gastroenteritis (AGE) affects all age groups alike, is a common cause of hospitalization worldwide and is the most common known cause of preventable acute kidney injury. Acute Kidney Injury (AKI) may be defined as a sudden decrease in kidney function, which results in reduced filtration capability of the kidneys, accumulation of waste products and their resultant clinical manifestations. Early detection of AKI caused by AGE can significantly decrease mortality rates. In Khost, studies investigating the incidence of AKI in AGE Patients are limited; thus, we aimed to fill this knowledge gap.
Materials and Methods: Aprospective observational study was conducted on 79 patients with AKI secondary to acute gastroenteritis admitted to Sheikh Zayed University Teaching Hospital Khost, Afghanistan , in 3 months duration from July 2023 to September 2023. Data were analyzed using SPSS 28.
Findings: In this study, 79 individuals were enrolled, including 58.2% male and 41.8% female. Of them, 79 patients with acute gastroenteritis, 40 (50.6%) had acute renal failure (ARF). Hypertension was the most common type of comorbidity 10 (12.6%), followed by diabetes mellitus 3 (3.8%). Diarrhea was the most commonly reported gastrointestinal symptom among the patients (78.5%), followed by vomiting (58.2%) and dysentery (20.3%). Dehydration was reported in all patients. Severe dehydration (48.1%) was the most common among patients with AGE-induced ARF. The proportion of patients with diarrhoea (90% vs. 66%, P<0.012) was significantly higher among patients with ARF than in those without ARF. Patients older than 40 years had a significantly higher frequency of ARF (67.5%) as compared to patients less than 40 years of age (13.5%) (P = 0.000). The median serum creatinine, sodium, and potassium levels in patients with age related ARF were 4.1mg/dl, 130mEq/L and 4.3 mEq/L, respectively. The serum creatinine level was higher in those with ARF (P = 0.490).
Conclusion: The study concluded that the incidence of acute kidney injury in patients presenting with acute gastroenteritis to Sheikh Zayed University Teaching Hospital is 40 (50.6%), due to hypovolemia caused by fluid losses in acute diarrheal illnesses. It can be prevented by prompt diagnosis and treatment by fluid administration.
Downloads
All the articles published in JAPSR are distributed under a creative commons license (CC BY-NC-SA 4.0)
Under this license, you are free to:
- Share- copy and redistribute the material in any medium or format for any purpose, even commercially.
- Adapt- remix, transform, and build upon the material for any purpose, even commercially.
The licensor cannot revoke these freedoms as long as you follow the license terms.
- Attribution — You must give appropriate credit , provide a link to the license, and indicate if changes were made . You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- NonCommercial — You may not use the material for commercial purposes .
- ShareAlike — If you remix, transform, or build upon the material, you must distribute your contributions under the same license as the original.
- No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.
Copyright policy
The journal allows the author(s) to hold the copyright of their work. That means the authors do not need to transfer the copyright of their work to the journal. However, the authors grant JAPSR a license to publish the article and identify itself as the original publisher.
Licensing policy
The journal allows the author(s) to hold the copyright of their work. That means the authors do not need to transfer the copyright of their work to the journal. However, the authors grant JAPSR a license to publish the article and identify itself as the original publisher.
