A CRITICAL REVIEW ON NANOEMULSION: ADVANTAGES, TECHNIQUES AND CHARACTERIZATION

Mrs. Gunjan Pranav Malode; Sarin A Chauhan; Shivam A Bartare; Lochana M Malode; Jagdish V Manwar; Ravindra L Bakal

doi:10.31069/japsr.v4i3.2

Mrs. Gunjan Pranav Malode Assistant Professor, IBSS’s Dr. Rajendra Gode Institute of Pharmacy, Amravati-444 602, Maharashtra, India
Sarin A Chauhan IBSS’s Dr. Rajendra Gode Institute of Pharmacy, Amravati-444 602, Maharashtra, India
Shivam A Bartare IBSS’s Dr. Rajendra Gode Institute of Pharmacy, Amravati-444 602, Maharashtra, India
Lochana M Malode IBSS’s Dr. Rajendra Gode Institute of Pharmacy, Amravati-444 602, Maharashtra, India
Jagdish V Manwar IBSS’s Dr. Rajendra Gode Institute of Pharmacy, Amravati-444 602, Maharashtra, India
Ravindra L Bakal IBSS’s Dr. Rajendra Gode Institute of Pharmacy, Amravati-444 602, Maharashtra, India

DOI https://doi.org/10.31069/japsr.v4i3.2

Abstract

Nanoemulsions have small droplet size and are kinetically stable colloidal systems. These are the thermodynamically stable isotropic system in which two immiscible liquids are mixed to form a single phase by means of appropriate surfactant and cosurfactant. Nanoemulsion droplet sizes fall typically in the range of 20–200 nm and shows narrow size distribution. They have enhanced functional properties in comparison to conventional emulsions. The composition and structure of the nanoemulsions can be controlled for the encapsulation and effective delivery of bioactive lipophilic compounds. Nanoemulsions have potential application in the food industry for the delivery of nutraceuticals, coloring and flavoring agents, and antimicrobials. This review aims to provide consolidated information regarding various formulation and characterization techniques developed for nanoemulsions. Various characterization techniques for nanoemulsions include determination of entrapment efficiency, particle size, polydispersity index, zeta potential as well as characterization through differential scanning calorimetry, Fourier-transform infrared spectroscopy and transmission electron microscopy.

Keywords: Nanoemulsions, Characterization techniques, self-emulsifying formulation, Self-emulsifying drug delivery system, Bioavailability

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